Popular Destinations
- Mexico
- Caribbean
- Las Vegas
- Orlando
- Hawaii
- Florida
- New York City
- Costa Rica
- New Orleans
- San Francisco
Holiday Inn St. Louis South Interstate 55 is a business-friendly St. Louis hotel in the business district and local attractions include Grants Farm, Ulysses S. Grant National Historic Site, and Laumeier Sculpture Park. Regional points of interest also include Missouri Botanical Gardens and Arboretum and Anheuser-Busch Brewery. Read More About Holiday Inn St. Louis South Interstate 55

